Caldwell Biomedical Electronics
Physiological Instrumentation Design
Biomedical Engineering Consultation
Hurricane, West Virginia 25526
304-757-8344 caldbio@earthlink.net
Caldwell Biomedical Electronics offers custom design of biomedical research instrumentation as well as several standard instruments for cardiovascular and neurophysiological research. These devices include pressure and force transducer amplifiers (bridge amps), biopotential amplifiers, animal temperature controllers, microperfusion pumps, electrical, mechanical and thermal stimulators, and biotelemetry systems.
All of our instuments are self-contained, non-modular and 120 VAC wall-current powered. Our tansducer amplifiers will input any half-bridge or full-bridge resistive pressure or force (or other parameter) transducer, such as the older Grass or Statham models and the newer semiconductor types. Full instuctions on inputting any bridge-type resistive transducer are included in the amplifier instruction and technical manual.
Our design and fabrication services can provide custom-designed electronic instrumentation for specialized physiological research. We have design experience in ultrasonic blood flow measurement, implanted cardiovascular instrumentation, computer data acquisition, biotelemetry and several other areas. Please contact us to discuss your specific biomedical instrumentation needs.
Product List
These instruments are not to be used with human subjects; they are supplied only for non-clinical scientific and industrial applications.
Transducer Amplifier Model 2000
Amplification of pressure, force or strain transducer signals Differential input and excitation for full or half-bridge resistive transducers
A -50 to 300 mmHg pressure transducer, with wired DIN connector, or equivalent, is supplied with each amplifier. See Model TA2000D below for transducer illustration. The output of this semiconductor transducer is 5 uV/Volts Excitation/mmHg, which is the industry standard for this type of research-grade pressure gauge.
Gain adjustable 500-5000; 0-150 Hz bandwidth, 125dB CMR
Easy calibration of integer voltage output per unit transduced, i.e., 0.5 Volts per mmHg. Ten-turn, numeric-scaled, gain control permits accurate return to various calibrations, or setting of calibration multipliers.
Normal and averaged output voltage relationship is 1:1
One channel standard; two, three or four channel versions available
Individual channel gain and transducer balance controls
Switch-selected 5 volts DC to outputs for recording system calibration
Output and averaged output simultaneously available at front panel BNC connectors. Averaged output cutoff frequency is 0.12 Hz
Five-pin DIN front panel input connector. GrassTM or other connector is optional
Transducer excitation load resistance may be any value above 200 ohms
Input impedance: 1000 megohms. Output impedance: less than one ohm
Noise: 2.5 microvolts p-p max. 0.1 - 1000 Hz, referenced to shorted inputs
Transducer excitation: 5 Volts DC
Maximum signal output: +/- 10 volts into 2000 ohms or greater load impedance
| $490 | | | | | | | | | | | | | | | | |
Available Options:
A. Accessory input adapter cable wired for any bridge-type resistive transducer and connector
B. Front panel input connector changed from DIN type to any other standard transducer connector. Space limitations may apply.
Digital Readout Transducer Amplifier Model 2000D



Specifications same as Model 2000 above, with addition of digital output display
Bright red light-emitting-diode (LED) numeric display is readable over a much wider viewing angle and distance range than dim liquid crystal displays (LCD)
A -50 to 300 mmHg pressure transducer, with wired DIN connector, as shown, is supplied with each amplifier
Maximum digital readout of 1999, with decimal point position selected by rear panel switch. The amplifier gain control calibrates the amplifier to display transduced unit parameters, which simultaneously sets both outputs to an integer voltage/unit measured relationship. The simulated pressure readout in the illustration is 108.2 mmHG.
| $680
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Transducer, General Purpose and Biopotential Amplifier Model 2100
Amplification of pressure, force or other transducer signals. Electrocardiogram and neurosignal amplification. The amplifier may also be used for amplification, display, differentiation and averaging of non-ECG cardiovascular signals from blood flowmeters, dimension gages, etc.
Gain adjustable 1-5000; 0-150 Hz bandwidth (non-ECG or neural mode), 125dB CMR
One channel standard; two, three or four channel versions available
Digital red LED panel meter readout of transducer measurements
Analog voltage output for input to computer data acquisition systems or recorders
Differential input for transducer, ECG, or nerve signals. Low-gain single-ended input also on front panel. Front panel selection of AC or DC coupling. ECG or neural bandwidths are also switch-selected.
Derivative and average outputs; dv/dt and averaging frequencies are suitable for cardiovascular signals such as arterial pressure, and singals from other instuments, such as blood flow and heart dimension meters.
Individual channel gain and transducer balance controls
Five-pin DIN front panel input connector
Other electrical specifications per Model 2000
| $690
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Options and accessories:
A. Heart rate meter with selectable internal or external triggering
B. Additional low-pass output filter; specified frequency 25 to 5,000 Hz
C. Neural action potential RMS output
D. 12-lead electrocardiogram input switch, connector, and cable
E. Input adapter cables for any type transducer connector
Eight-channel Transducer Amplifier Model 2200

Amplification and excitation of resistive bridge pressure, force or strain transducers
Individual channel bandwidths selectable 0-25 or 0-100 Hz Fixed gain of 1000; differential input, 125 dB CMR
Five-pin DIN front panel input connector
Other electrical specifications per Model 2000
Figure shown is 16-channel option
| $2970 (8-channel)
| | | | | | |
Options and accessories:
A. Input adapter cables for any type transducer connector
B. Transducer balancing by digital input signal from data acquisition software
C. Transducer balancing by front panel 10-turn potentiometer (standard)
C. Sixteen channels
D. Variable gain 0-5000
E. Output low-pass filters at any specified frequency from 25 to 5,000 Hz
Electrocardiogram Amplifier Model 2300
Single channel with lead I, II, III, AVR, AVL, AVF, V and STD input selector switch
Internal battery operated
Gain adjustable 100 - 2000; 130 dB CMR, 100 megohm input impedance
Voltage output for driving computer data acquisition systems or chart recorder
Standard EKG frequency response
Push-button switch supplies 1 millivolt reference input
| $2950
| | | | | | |
DC Heat/Cool Proportional Animal Temperature Controller Model 2400

Low-noise DC output eliminates electrical interference produced by AC type controllers
DC 0-12 volt, 40-watt output for animal heating pads, microscope stage heaters and perfusion chambers
Temperature measurement and control accuracy of +/- 0.1 oC from 0 to 40 oC
Uses standard YSI 400 series thermistor temperature transducers
Analog 0.1 volt/oC measured temperature output for recording
Figure shown is four-controller option, configured for driving four individual animal heater pads.
| $785 (Single controller)
| | | | | | |
Options and Accessories:
A. Higher power 65 watt DC output
B. Bipolar output for driving Peltier modules in both cooling and heating modes
C. Feedback phase reversal switch for driving either resistive heating devices or Peltier modules in cooling mode. Option B is not necessary for this cooling-only task addition. Metering and output scaled accordingly
D. Type K thermocouple temperature measurement and -25 to +60 oC operation
E. External input temperature control programmability
F. Two, three, or four separate controllers in one cabinet
G. Heating pads and custom heating or cooling devices
AC Heat/Cool Temperature Controller Model 2500


Proportional-integral-derivative (PID) control with autotune for use with any thermal load.
Employs Omega (TM) CN77000 microprocessor temperature controller
1000 watt, 0-120 volt proportional output for general laboratory temperature control tasks
Control of any 120 volt AC heating or cooling device
Basic accuracy: +/- 0.5oC. Control accuracy is dependent on thermal coupling of heating/cooling device to load; generally +/- 2.0oC from -129 to 990oC
Actual and set temperatures displayed simultaneously on individual 4-digit readouts
Inputs standard thermocouple and RTD temperature transducers (specify type for correct back panel connector)
One each heat ramp and soak time, both adjustable from 0 to 100 hours
Over or under-temperature alarm output signal - absolute or degrees deviation from setpoint
Accepts voltage or current inputs for control of any transducer and controllable physical variable
| $685
| | | | | | | | | | |
Options and accessories:
A. 0-10 VDC or temperature output for recording load temperature
B. RS-485 output
C. AC-DC converter for driving Peltier cooling modules from controller main output
D. Custom heating or cooling devices
Universal Physiological Amplifier/ Summer/Filter/Averager/Differentiator Model 2600
Three DC-5000 Hz individual amplifiers; two single-ended input and one differential input
Amplifier gains individually adjustable from 1 to 100
Amplifier frequency responses individually specifiable for low, band or high pass filtering
One summing amplifier with three single-ended summed inputs; Vout=Vin1+Vin2+Vin3
Two differentiator amplifiers with individually specifiable dVin/dt output gains
All amplifier input impedances 100 megohms
Amplifier output range +/- 10 volts @ 5 ma
Typical applications: biopotential and general data signal amplification, noise filtering, averaging (low-pass filtering), signal offset elimination, generating rates of change of blood pressure or heart dimension waveforms, summing or subtracting physiological data signals, data signal baseline shifting
| $760
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Constant Pressure Perfusion Pump Model 3000
Pressure generation and measurement from 0 to 200 mmHg
Pressure and flow output signals for recording and use in laminar flow resistance computation
Digital display of set point and measured pressure
Maximum flow rate: 500 microliters/minute
Measurement and control accuracy: +/- 0.50 mmHg
| $7850
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E-mail Message to Caldwell Biomedical Electronics: caldbio@earthlink.net
Any of the above products can be custom modified for your specific application.
Please contact us at any time to discuss your instrumentation needs.
Thank you,
Mort Caldwell
W. Morton Caldwell, BSEE, MS, PE